|Document ID (ISN)||48772|
|Convention or series no.
||Arbete och Hälsa 1986:8
||Nordic Expert Group for Documentation of Threshold Limit Values - 65. Allyl alcohol
||Nordiska expertgruppen för gränsvärdesdokumentation - 65. Allylalkohol [in Swedish]|
||Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1986. 38p. Illus. 81 ref.
||A critical review of the literature relevant to discussions for an exposure limit is presented. In man the earliest symptom of exposure to allyl alcohol is irritation of the mucous membranes. Damage to internal organs has not been registered. In animal experiments the liver was found to be the most severely damaged organ, while damage to other organs was slight. In long-term experiments a certain adaptation was demonstrated in that the liver when damaged may heal in spite of continued exposure. There is no information on teratogenicity or carcinogenicity. The metabolite glycidaldehyde may have slight carcinogenic properties. Allyl alcohol is mutagenic in the Ames test. A threshold limit value should prevent mucous membrane irritation.
||mutagenic effects; threshold limit values; determination of exposure limits; allyl alcohol; hepatotoxic effects; irritants
||Nordic Countries; criteria document; animal experiments
||F - Information notes, codes of practice, standards
||Toxic and dangerous substances
|Broad subject area(s)
||Antifertility and prenatal effects
Genetic factors in reaction to exposures
Occupational exposure limits