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Document ID (ISN)48772
CIS number 87-1423
ISBN(s) 91-7464-294-4
Year 1986
Convention or series no. Arbete och Hälsa 1986:8
Author(s) Swensson A.
Title Nordic Expert Group for Documentation of Threshold Limit Values - 65. Allyl alcohol
Original title Nordiska expertgruppen för gränsvärdesdokumentation - 65. Allylalkohol [in Swedish]
Bibliographic information Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1986. 38p. Illus. 81 ref.
Abstract A critical review of the literature relevant to discussions for an exposure limit is presented. In man the earliest symptom of exposure to allyl alcohol is irritation of the mucous membranes. Damage to internal organs has not been registered. In animal experiments the liver was found to be the most severely damaged organ, while damage to other organs was slight. In long-term experiments a certain adaptation was demonstrated in that the liver when damaged may heal in spite of continued exposure. There is no information on teratogenicity or carcinogenicity. The metabolite glycidaldehyde may have slight carcinogenic properties. Allyl alcohol is mutagenic in the Ames test. A threshold limit value should prevent mucous membrane irritation.
Descriptors (primary) mutagenic effects; threshold limit values; determination of exposure limits; allyl alcohol; hepatotoxic effects; irritants
Descriptors (secondary) Nordic Countries; criteria document; animal experiments
Document type F - Information notes, codes of practice, standards
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Alcohols
Genetic factors in reaction to exposures
Occupational exposure limits