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CISDOC database

Document ID (ISN)48640
CIS number 87-1393
ISBN(s) 0-11-883859-8
Year 1986
Convention or series no. Toxicity Review TR 14
Author(s) Woodward K.N., Smith A.M., Mariscotti S.P., Tomlinson N.J.
Health and Safety Executive
Title Review of the toxicity of the esters of o-phthalic acid (phthalate esters)
Bibliographic information HM Stationery Office Publications Centre, PO Box 276, London SW8 5DT, United Kingdom, 1986. 183p. 604 ref. Price: ú15.20.
Abstract This review covers: identities; absorption, biotransformation, distribution and excretion; animal toxicity (acute toxicity, irritation, and sensitisation, subacute toxicity, hypolipaemic and related effects, hepatic effects, effects on reproductive organs, mutagenicity, chronic toxicity and carcinogenicity); metabolism and effects in humans (acute toxicity, irritation and sensitisation, long-term exposure, other studies).
Descriptors (primary) United Kingdom; phthalates; toxicity evaluation; harmful substances; toxicology
Descriptors (secondary) mutagenic effects; benzyl butyl phthalate; bis(2-ethylhexyl) cyclohexene-1,2-dicarboxylate; monomethyl phthalate; butyl octyl phthalate; bis(3-methylbutyl) phthalate; literature survey; antifertility effects; acute toxicity; hepatotoxic effects; metabolic process; dipentyl phthalate; bis(butoxyethyl) phthalate; diphenyl phthalate; bis(ethylhexyl) phthalate; dioctyl phthalate; diisooctyl phthalate; dinonyl phthalate; decyl octyl phthalate; diisopropyl phthalate; diethylene glycol bis(butyl phthalate); butoxycarbonylmethyl butyl phthalate; lipids; dimethyl phthalate; 2-ethoxy-2-oxoethyl methyl phthalate; diethyl phthalate; 2-ethoxy-2-oxoethyl ethyl phthalate; bis(methoxyethyl) phthalate; diallyl phthalate; dibutyl phthalate; butyl decyl phthalate; monobutyl phthalate; diisobutyl phthalate; dihexyl phthalate; dicyclohexyl phthalate; irritation; animal experiments; long-term exposure; carcinogenic effects; data sheet; mono(2-ethylhexyl) phthalate; di-n-heptyl phthalate; toxic effects
Document type E - Books, reports, proceedings
Subject(s) Chemicals, plastics and rubber
Broad subject area(s) Chemical safety
Browse category(ies) Genetic factors in reaction to exposures
Phthalates
Esters and salts