|Document ID (ISN)||48615|
|Convention or series no.
||DHHS (NIOSH) Publication No.87-101
||The development and application of algorithms for generating estimates of toxicity for the NOHS data base
||National Institute for Occupational Safety and Health, Centers for Disease Control, Robert A. Taft Laboratories, 4676 Columbia Parkway, Cincinnati, OH 45226, USA, Jul. 1986. 96p. 35 ref. Appendices.
||Four algorithms were developed to provide estimates of LD50 (oral, rat), mutagenicity, carcinogenicity, and teratogenicity. The models were tested against available data, then applied to substances in the National Occupational Hazard Survey (NOHS). The estimates are useful for assessing toxicity where little or no data are available. They contain a certain degree of unavoidable error and are intended only for rank-ordering a list of compounds according to relative toxicity or as a part of an overall process of selecting, testing, and evaluating chemical compounds for toxicity.
||USA; hazard evaluation; computer analysis; chemical hazards; toxicity evaluation
||toxic effects; mutagens; teratogens; report; carcinogens
||E - Books, reports, proceedings
||Toxic and dangerous substances
|Broad subject area(s)