|Document ID (ISN)||48207|
|ISSN - Serial title
||0096-1736 - Journal of Occupational Medicine
|Convention or series no.
||Séguin P., Allard A., Cartier A., Malo J.L.
||Prevalence of occupational asthma in spray painters exposed to several types of isocyanates, including polymethylene polyphenylisocyanate
||Apr. 1987, Vol.29, No.4, p.340-344. Illus. 15 ref.
||The prevalence of occupational asthma was assessed in 4 paint shops of a large assembly plant where 51 employees were exposed to several types of isocyanates, including polymethylene polyphenylisocyanate (PPI). Three employees were first referred by their physician for asthma symptoms. A questionnaire was administered to the other 48 employees. Seven of these were suspected of having work-related asthma. Airway hyperexcitability to inhaled histamine was demonstrated in these 10 subjects (3 referred and 7 screened). The diagnosis of occupational asthma was confirmed in 6 subjects (3 referred and 3 screened) through specific inhalation challenges in the laboratory to a paint system component containing PPI. Thus, the prevalence of occupational asthma was 11.8% in these paint shops using several types of isocyanates, including PPI.
||isocyanates; paint spraying; allergic asthma
||Canada; methylene diisocyanate; hexamethylene diisocyanate; polymethylenepolyphenylene isocyanate; 2,4-tolylene diisocyanate; epidemiologic study; isophorone diisocyanate
||D - Periodical articles
||Chemicals, plastics and rubber
|Broad subject area(s)
||Industries and occupations
||Diseases of the respiratory system (except for pneumoconiosis & similar)