ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)48207
CIS number 87-949
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1987
Convention or series no.
Author(s) Séguin P., Allard A., Cartier A., Malo J.L.
Title Prevalence of occupational asthma in spray painters exposed to several types of isocyanates, including polymethylene polyphenylisocyanate
Bibliographic information Apr. 1987, Vol.29, No.4, p.340-344. Illus. 15 ref.
Abstract The prevalence of occupational asthma was assessed in 4 paint shops of a large assembly plant where 51 employees were exposed to several types of isocyanates, including polymethylene polyphenylisocyanate (PPI). Three employees were first referred by their physician for asthma symptoms. A questionnaire was administered to the other 48 employees. Seven of these were suspected of having work-related asthma. Airway hyperexcitability to inhaled histamine was demonstrated in these 10 subjects (3 referred and 7 screened). The diagnosis of occupational asthma was confirmed in 6 subjects (3 referred and 3 screened) through specific inhalation challenges in the laboratory to a paint system component containing PPI. Thus, the prevalence of occupational asthma was 11.8% in these paint shops using several types of isocyanates, including PPI.
Descriptors (primary) isocyanates; paint spraying; allergic asthma
Descriptors (secondary) Canada; methylene diisocyanate; hexamethylene diisocyanate; polymethylenepolyphenylene isocyanate; 2,4-tolylene diisocyanate; epidemiologic study; isophorone diisocyanate
Document type D - Periodical articles
Subject(s) Chemicals, plastics and rubber
Broad subject area(s) Industries and occupations
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Allergies
Isocyanates
Cyano compounds
Surface treatment