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CISDOC database

Document ID (ISN)47822
CIS number 87-523
ISSN - Serial title 1000-7164 - Industrial Health and Occupational Diseases
Year 1985
Convention or series no.
Author(s) Yuan C., Zhang D.
Title Frequency of lymphocyte sister chromatid exchanges in coke-oven workers
Original title Jiaoluzuoye gongren waizhou xuelinbaxibao zimeiranseti huhuan [in Chinese]
Bibliographic information 1985, Vol.11, No.6, p.336-338. 6 ref.
Abstract The analysis of sister chromatid exchange (SCE) is a useful technique for the study of genetic damage in humans exposed to environmental mutagens and carcinogens. In the present study, lymphocyte sister chromatid exchange frequencies were determined for 12 long-term coke-oven workers and 20 controls. The duration of exposure to the coke oven emissions ranged from 15 to 32 years. The mean SCE frequency for the exposed group was 13.04 ▒ 1.47 SCEs per cell and that for the control group was 8.82▒1.26. The increased SCE frequency in coke-oven workers may be related to the long-term exposure to coke-oven emissions.
Descriptors (primary) mutagenic effects; iron and steel industry; carcinogenic effects; coke ovens
Descriptors (secondary) genetic effects
Document type D - Periodical articles
Subject(s) Metal production and metalworking
Broad subject area(s) Industries and occupations
Browse category(ies) Antifertility and prenatal effects
Iron and steel industry
Genetic factors in reaction to exposures