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Document ID (ISN)46861
CIS number 86-1681
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 1985
Convention or series no.
Author(s) D°ssing M., Skinh°j P.
Title Occupational liver injury - Present state of knowledge and future perspective
Bibliographic information 1985, Vol.56, No.1, p.1-21. 164 ref.
Abstract Epidemiological studies using immunological methods have mapped the occurrence of hepatitis B among health-care personnel and thereby made rational, effective preventive precautions possible, and hepatitis B vaccine has offered further improvements. However, in the field of chemically-induced occupational liver damage, only a few of the thousands of industrial chemicals have been sufficiently tested for hepatotoxicity and the list of suspected and confirmed hepatotoxic agents is still growing. The example of vinyl chloride-induced liver disease among plastics workers calls for intensified activities in the field of occupational toxicology. However, the clinical, biochemical, and morphological features of liver disease are often vague and unspecific. A non-invasive, convenient quantitative liver function test is needed. Circumstantial evidence and a few epidemiological studies suggest that so-called cryptogenic liver diseases, such as liver cirrhosis, may be caused by occupational exposure to chemicals.
Descriptors (primary) hepatic diseases
Descriptors (secondary) literature survey; harmful substances; toxic hepatitis; toxic substances; hepatitis; infectious hepatitis
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Liver diseases
Bacterial and parasitic diseases
Viral diseases (other than aids)