| Document ID (ISN) | 46734 |
| CIS number |
86-1657 |
| ISBN(s) |
91-7464-242-1 |
| Year |
1984 |
| Convention or series no. |
Arbete och Hälsa 1984:49
|
| Author(s) |
Hogstedt C., Aringer L., Gustavsson A. |
| Title |
Ethylene oxide and cancer - review of the literature and follow-up of two studies |
| Original title |
Etylenoxid och cancer - litteraturöversikt och uppföljning av två epidemiologiska studier [in Swedish] |
| Bibliographic information |
Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1984. 32p. 34 ref. |
| Abstract |
The rapidly growing literature on genotoxic effects in humans and animals of exposure to ethylene oxide is reviewed. Furthermore, two Swedish studies published in 1979 were followed up regarding mortality and cancer incidence. One more case of leukaemia was detected in a group of 203 exposed packers in addition to the two previously described cases of malignancies from the haematopoietic system and a non-Hodgkin lymphoma. Among 89 ethylene oxide operators with mixed exposure, another case of leukaemia was found in addition to two previously described cases. Furthermore, the risk of stomach cancer was greatly increased in the production group. Epidemiological, cytogenetic and animal studies support the view that ethylene oxide in low concentrations increases the risk of cancer after continuous exposure and possibly also after intermittent exposure. |
| Descriptors (primary) |
mortality; neoplasms; carcinogenic effects; ethylene oxide |
| Descriptors (secondary) |
literature survey; gastrointestinal cancer; Sweden; leukaemia |
| Document type |
E - Books, reports, proceedings |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Ethers
Ethylene oxide
|
