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Document ID (ISN)46352
CIS number 86-1095
ISSN - Serial title 1000-7164 - Industrial Health and Occupational Diseases
Year 1985
Convention or series no.
Author(s) Yuan C.
Title Frequency of lymphocyte sister chromatid exchanges in coke oven workers
Bibliographic information 1985, Vol.11, No.6, p.336-338.
Abstract The analysis of sister chromatid exchange (SCE) might be a useful technique for the study of genetic damage in humans exposed to environmental mutagens and carcinogens. In the present study, lymphocyte sister chromatid exchange frequencies were determined for 12 long-term coke oven workers and 20 controls. The duration of exposure to the coke oven emissions ranged from 15 to 32yrs. The mean SCE frequency for the exposed group was 13.-4▒1.47 SCEs per cell and that for the control group was 8.82▒1.26 SCEs per cell. The difference was highly significant (P<0.0001). The increased SCE frequency in coke oven workers may be related to long-term exposure to coke oven emissions.
Descriptors (primary) coal by-products industry; chromosome changes; coke ovens
Descriptors (secondary) carcinogens; mutagens
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Chemical industry
Genetic factors in reaction to exposures