|Document ID (ISN)||46115|
|Convention or series no.
||Environmental Health Criteria 56
||World Health Organization, Distribution and Sales Service, 1211 Genève 27, Switzerland, 1985. 53p. 99 ref. Price: SF.8.00.
||Exposure of man to propylene oxide mainly occurs through inhalation at the workplace. Taking into account the body of available data - the alkylating nature of propylene oxide, the formation of DNA adducts, the positive response in in vitro mutagenesis assays, the carcinogenic effects in animals at the sites of entry into the body, and the absence of adequate data on cancer in human beings - propylene oxide should be regarded as if it presented a carcinogenic risk for man, and levels in the environment should be kept as low as feasible.
||toxicology; hazard evaluation; propylene oxide
||mutagenic effects; carcinogenic effects; animal experiments
||E - Books, reports, proceedings
||Toxic and dangerous substances
|Broad subject area(s)
Genetic factors in reaction to exposures