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Document ID (ISN)46015
CIS number 86-760
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1986
Convention or series no.
Author(s) Groeseneken D., Van Vlem E., Veulemans H., Masschelein R.
Title Gas chromatographic determination of methoxyacetic and ethoxyacetic acid in urine
Bibliographic information Jan. 1986, Vol.43, No.1, p.62-65. Illus. 10 ref.
Abstract Methoxyacetic acid (MAA) and ethoxyacetic acid (EAA), the major metabolites of ethylene glycol monomethyl ether (methoxyethanol) and ethylene glycol monoethyl ether (cellosolve), respectively (and of their acetates), were determined by gas chromatography after extraction from urine and methylation using 2-furoic acid (2-FA) as an internal standard. Mean recovery rates from urine of both MAA and EAA (expressed as the response in area percentage relative to the internal standard) were linearly related to exposure levels in the range of 1-100mg/L of urine. The determination method is judged to be rapid, selective and sensitive and can be used to estimate exposure levels to the ethers concerned.
Descriptors (primary) ethoxyethanol; methoxyethanol; determination in urine; dosimetry; gas chromatography; exposure evaluation
Descriptors (secondary) urinary metabolites; methoxyacetic acid
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Exposure evaluation
Glycol ethers