| Document ID (ISN) | 45684 |
| CIS number |
86-417 |
| ISSN - Serial title |
0304-3894 - Journal of Hazardous Materials |
| Year |
1985 |
| Convention or series no. |
|
| Author(s) |
Serge W.F. |
| Title |
The toxicity of methylisocyanate for rats |
| Bibliographic information |
Dec. 1985, Vol.12, No.3, p.309-311. Illus. 3 ref. |
| Abstract |
The results of previous experiments on rats are used to derive a concentration-time mortality-response relationship. Contrary to gases such as chlorine or ammonia whose lethality depends on concentration, it seems that in the case of methylisocyanate, the duration of exposure is dominant in determining the mortality response. A prolonged exposure to MIC may have therefore been the cause of the high number of victims in Bhopal in India. One should consider in this connection that MIC does not have a well recognisable odour at concentrations up to 24mg/m3. |
| Descriptors (primary) |
methyl isocyanate; dose-response relationship; lethal concentration 50; toxicology |
| Descriptors (secondary) |
odour threshold; disasters; animal experiments |
| Document type |
D - Periodical articles |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Isocyanates
Cyano compounds
|
