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CISDOC database

Document ID (ISN)45463
CIS number 86-126
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1985
Convention or series no.
Author(s) Steenland K., Carrano A., Clapp D., Ratcliffe J., Ashworth L., Meinhardt T.
Title Cytogenetic studies in humans after short-term exposure to ethylene dibromide
Bibliographic information Oct. 1985, Vol.27, No.10, p.729-732. 25 ref.
Abstract Ethylene dibromide (EDB) has been shown to increase sister chromatid exchange in animal cells in vitro, but its cytogenic effects in humans have not been previously studied. 14 workers who used a solution of EDB to spray felled pine trees to kill pine beetles were tested for the presence of SCE and chromosomal aberrations in peripheral blood. 6 non-exposed workers were also tested. The sprayers were exposed to an average EDB concentration of 60 ppb (8h TWA). The workers sprayed EDB for only 5 to 26 days during the summer months. After adjusting for smoking and the use of prescription drugs, there was no statistically significant difference between the frequencies of either SCEs or chromosomal aberrations before and after spraying.
Descriptors (primary) forestry and logging; dibromoethane; cytological effects; chromosome changes
Descriptors (secondary) USA; epidemiologic study; dibromomethane
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Halogenated hydrocarbons
Forestry and logging
Genetic factors in reaction to exposures