| Document ID (ISN) | 45425 |
| CIS number |
86-181 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
1984 |
| Convention or series no. |
|
| Author(s) |
Omae K. |
| Title |
Two-year observation of pulmonary function in workers exposed to low concentrations of toluene diisocyanate |
| Bibliographic information |
1984, Vol.55, No.1, p.1-12. 26 ref. |
| Abstract |
Pulmonary effects were investigated in 106 workers exposed to toluene diisocyanate (TDI) and 39 referents in 1980 and in 64 exposed workers and 21 referents in the 2-year follow-up study ending in 1982. Individual, time-weighted average (TWA) exposure concentrations measured by personal monitors averaged approximately 0.001ppm in each year. No differences were observed in the means of the pulmonary functions and their individual daily changes between the TDI workers and the referents. The incidence of respiratory symptoms in the TDI workers was not significantly higher than in the referents, but there was irritation of the eyes and throat probably due to peak exposure to TDI and/or co-existing irritants. These results suggest that TDI exposure at the 0.001ppm level does not produce adverse pulmonary effects except in cases of hypersensitivity. |
| Descriptors (primary) |
chemical industry; tolylene diisocyanate; subthreshold exposure; long-term exposure; pulmonary function |
| Descriptors (secondary) |
2,4-tolylene diisocyanate; functional respiratory disorders; comparative study; plastics industry; respiratory function tests |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Chemical industry
Isocyanates
Cyano compounds
|
