| Document ID (ISN) | 45410 |
| CIS number |
86-180 |
| Year |
1983 |
| Convention or series no. |
ECETOC Monograph No.5
|
| Title |
Identification and assessment of the effects of chemicals on reproduction and development (Reproductive toxicology) |
| Bibliographic information |
European Chemical Industry Ecology and Toxicology Centre, Avenue Louise 250, Boîte 63, 1050 Bruxelles, Belgium, Dec. 1983. 32p. Illus. 10 ref. |
| Abstract |
Contents: introduction (motivation of the study); the reproductive cycle in mammals; influence of exogenous agents on reproduction; some characteristics of the reproductive toxic effects of chemicals; current status of testing for reproductive toxicity (tests in current guidelines and other techniques; epidemiology); significance of experimental animal data and their relevance to man; areas deserving further investigation; summary and conclusions (interspecies differences in response to chemicals mean that testing protocols must be developed for each substance of interest, but many of the difference between the guidelines of different countries could be eliminated). In appendixes: glossary; list of leading guidelines for reproductive toxicity testing; recommendations from some leading guidelines. |
| Descriptors (primary) |
antifertility effects; extrapolation animal man; toxicity evaluation; toxicology |
| Descriptors (secondary) |
epidemiologic study; round-up; animal experiments |
| Document type |
E - Books, reports, proceedings |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Antifertility and prenatal effects
Genetic factors in reaction to exposures
Toxicology
|
