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Document ID (ISN)45405
CIS number 86-176
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 1985
Convention or series no.
Author(s) Goh C.L., Ng S.K.
Title Photoallergic contact dermatitis to carbimazole
Bibliographic information Jan. 1985, Vol.12, No.1, p.58-59. 4 ref.
Abstract A dispensing assistant who worked in a pharmaceutical laboratory for 10 years developed recurrent rashes on exposed skin. Two years of detailed observation by the victim enabled him to correlate the recurrence of the rash with the production of 1 of 3 drugs in an adjoining area. Patch testing by medical personnel identified carbimazole, a thiourea derivative, as the agent responsible. A positive test was obtained only after exposure of the test site to the sun. Temporary transfer of the worker to another area during carbimazole tabletting prevented further episodes of the rash.
Descriptors (primary) thioureas; pharmaceutical industry; photosensitization dermatitis
Descriptors (secondary) carbimazole; case study
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Pharmaceutical industry
Skin diseases
Amides