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Document ID (ISN)45400
CIS number 86-171
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1984
Convention or series no.
Author(s) Sigova N.V., Blohin V.A.
Title Toxicological characteristics of chromium phosphate binders
Original title Toksikologičeskaja harakteristika hromofosfatnyh svjazujuščih [in Russian]
Bibliographic information June 1984, No.6, p.50-52. 4 ref.
Abstract Chromophosphate binders are expected to find wide use in refractories and pigments. Chromium phosphate itself and mixtures containing copper, nickel, calcium-nickel and calcium-aluminium chromates were administered topically, intragastrically and by inhalation to rabbits, mice and rats. The compounds were irritant, producing gastritis on ingestion and brochitis on inhalation. LD50s ranged from 0.31 to 4.30g/kg, depending on compound and species. The mixtures were more toxic than pure chromium phosphate. The following MACs are proposed: for chromium phosphate and copper chromophosphate 0.02mg/m3 as chromium; for calcium aluminium chromophosphate 0.01mg/m3 as chromic oxide; for nickel chromophosphate and calcium nickel chromophosphate 0.005mg/m3 as nickel.
Descriptors (primary) threshold limit values; USSR; nickel and compounds; copper and compounds; chromium and compounds; toxicology; chromium phosphate; chromophosphates; calcium and compounds; aluminium and compounds
Descriptors (secondary) irritants; bronchitis; chromates; animal experiments; gastritis
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Occupational exposure limits
Nickel and compounds
Copper and compounds
Inorganic substances