| Document ID (ISN) | 45396 |
| CIS number |
86-168 |
| ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
| Year |
1984 |
| Convention or series no. |
|
| Author(s) |
Uždavini Ė.R., Parfenova T.I., Mamaeva A.A., Gilev V.G. |
| Title |
Inhalation toxicity of anisole |
| Original title |
Toksičeskie svojstva anizola pri ingaljacionnom vozdejstvii [in Russian] |
| Bibliographic information |
June 1984, No.6, p.43-44. 4 ref. |
| Abstract |
Anisole, a solvent used in the synthesis of pharmaceuticals, had an LC50 of 3021mg/m3 in experiments with mice; no lethal concentration could be established for rats. The compound was primarily an irritant and narcotic, although dystrophic changes were found in the livers of experimental animals. Human volunteers exposed to 200mg/m3 experienced buring in the throat, irritation of the eyes and a foreign taste in the mouth. A MAC of 5mg/m3 is recommended. |
| Descriptors (primary) |
neurotoxic effects; threshold limit values; irritants; pharmaceutical industry; chemical industry; anisole; toxicology; USSR |
| Descriptors (secondary) |
human experiments; animal experiments |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Chemical industry
Pharmaceutical industry
Occupational exposure limits
Diseases of the nervous system
Ethers
|
