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Document ID (ISN)45392
CIS number 86-165
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1984
Convention or series no.
Author(s) Makarov I.A.
Title Sexual disorders in male workers occupationally exposed to methyl methacrylate and vinyl chloride
Original title Sostojanie seksual'noj sfery u rabočih-mužčin, podvergajuščihsja proizvodstvennomu vozdejstviju metilmetakrilata i vinilhlorida [in Russian]
Bibliographic information June 1984, No.6, p.19-23. 9 ref.
Abstract Questionnaire surveys of 198 workers in the plastics industry and 95 controls were supplemented with hormone assays in the case of 32 plastics workers and 10 controls. Both methyl methacrylate and vinyl chloride inhibit sexual activity. Vinyl chloride seems to act primarily via the central nervous system, while methyl methacrylate acts on the sex organs; both compounds produce toxic hypogonadism. Sexual dysfunction was seen in conjunction with other occupational diseases due to exposure to the monomers. The effects of methyl methacrylate disappear 1-2 years after cessation of exposure without special treatment; workers exposed to vinyl chloride should be treated with a testosterone preparation.
Descriptors (primary) vinyl chloride; methyl methacrylate; plastics industry; gonadotropic effects; neuro-endocrine effects; sexual disorders
Descriptors (secondary) hormone therapy; impotence
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the nervous system
Antifertility and prenatal effects
Genetic factors in reaction to exposures
Halogenated hydrocarbons
Plastics industry
Acrylates
Chemical industry