| Document ID (ISN) | 45286 |
| CIS number |
86-139 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
1984 |
| Convention or series no. |
|
| Author(s) |
Laurent C., Frederic J., Léonard A.Y. |
| Title |
Sister chromatid exchange frequency in workers exposed to high levels of ethylene oxide in a hospital sterilization service |
| Bibliographic information |
1984, Vol.54, No.1, p.33-43. 40 ref. |
| Abstract |
Blood samples were taken from a group of 25 subjects exposed to high levels of ethylene oxide (EO); the quantity of EO inhaled during the past 2 years was evaluated to fall between 500 and 5800mg. Compared to a control group, the exposed group demonstrated a significant increase in the sister chromatid exchange (SCE); the rise was 100% in certain individuals. Senior workers had the highest SCE mean levels. This observation shows that the effect of exposure to EO was sufficient to produce a genetic reaction, was cumulative and in some cases persistent. |
| Descriptors (primary) |
disinfection of equipment; chromosome changes; hospitals; ethylene oxide |
| Descriptors (secondary) |
analysis of chromosome aberrations |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Health care services
Ethylene oxide
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Ethers
|
