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CISDOC database

Document ID (ISN)45196
CIS number 85-1983
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1985
Convention or series no.
Author(s) Crebelli R., Paoletti A., Falcone E., Aquilina G., Fabri G., Carere A.
Title Mutagenicity studies in a tyre plant: in vitro activity of workers' urinary concentrates and raw materials
Bibliographic information July 1985, Vol.42, No.7, p.481-487. Illus. 22 ref.
Abstract Urine concentrates of 72 workers in an Italian tyre factory, and of 16 controls, were assayed to study the urinary mutagenicity of occupational exposure in the rubber industry. Smoking habits, but not occupation, were significantly related to urinary mutagenicity. 3 raw materials checked were weakly mutagenic in strain TA98 of Salmonella typhimurium: poly-p-dinitrosobenzene (in the absence of metabolic activation) and mixed diaryl-p-phenylendiamines and tetramethylthiuram disulfide (in the presence of metabolic activation).
Descriptors (primary) mutagenic effects; tyre manufacturing industry; rubber industry
Descriptors (secondary) Italy; determination in urine; smoking; tetramethylthiuram disulfide
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Rubber industry
Genetic factors in reaction to exposures