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CISDOC database

Document ID (ISN)44575
CIS number 85-1380
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1985
Convention or series no.
Author(s) Van Sittert N.J., De Jong G., Clare M.G., Davies R., Dean B.J., Wren L.J., Wright A.S.
Title Cytogenetic, immunological, and haematological effects in workers in an ethylene oxide manufacturing plant
Bibliographic information Jan. 1985, Vol.42, No.1, p.19-26. 21 ref.
Abstract Samples of blood were collected over a period of up to 14 years from 36 workers engaged in ethylene oxide (EO) manufacture and from 35 matched controls. There was a small positive correlation between length of employment in EO manufacturing and frequency of chromosome breaks and with the percentage of neutrophils in a differential white blood cell count. There was a small negative correlation between length of employment and the percentage of lymphocytes. None of these correlations had a significance for health. No correlations were found between EO exposure and the other biological parameters investigated.
Descriptors (primary) ethylene oxide; chromosome changes; biological effects; immunology; haematological effects
Descriptors (secondary) lymphocytes; long-term study; neutrophil changes
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Blood diseases
Antifertility and prenatal effects
Ethylene oxide
Genetic factors in reaction to exposures