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Document ID (ISN)44521
CIS number 85-1370
ISSN - Serial title 0016-9900 - Gigiena i sanitarija
Year 1984
Convention or series no.
Author(s) Medved' I.L.
Title Potential embryotoxic hazard of the herbicide betanal (experimental data)
Original title O potencial'noj opasnosti ėmbriotoksičeskogo dejstvija gerbicida betanala (ėksperimental'nye dannye) [in Russian]
Bibliographic information Apr. 1984, No.4, p.16-18. 8 ref.
Abstract When administered to rats in a single peroral dose of 2000mg/kg (0.5LD50) or in repeated inhalation doses of 40mg/kg (0.01LD50) at a concentration of 30mg/m3, betanal was embryotoxic and teratogenic. Changes were noted in the nucleic acid contents of certain organs of the mothers and offspring. The threshold concentration for embryotoxic action is 2mg/m3. A MAC of 0.5mg/m3 is recommended.
Descriptors (primary) embryotoxic effects; herbicides; threshold limit values; teratogenic effects; phenmedipham; toxicology; USSR
Descriptors (secondary) animal experiments
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Occupational exposure limits
Agricultural chemicals
Genetic factors in reaction to exposures