ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)44387
CIS number 85-1354
ISSN - Serial title 0025-7818 - Medicina del lavoro
Year 1984
Convention or series no.
Author(s) Camoni I., Cicero A.M., Di Muccio A., Dommarco R.
Title Measurement of urinary excretion of ethylenethiourea (ETU) in rats that have ingested Zineb
Original title Verifica della escrezione urinaria di etilentiourea (ETU) in ratti trattati con Zineb [in Italian]
Bibliographic information May-June 1984, Vol.75, No.3, p.207-214. Illus. 26 ref.
Abstract Urinary and faecal excretion of ETU, a metabolite of ethylene-bis-dithiocarbamic fungicides, was monitored in rats for 16 days after they were administered a single oral dose of Zineb. After 48h, 86% of the excreted ETU was in the urine, 14% in the faeces. Urinary excretion peaked at 24h after ingestion, at which time 52% of the total urinary ETU had been excreted. Low levels of ETU excretion continued in urine for the length of the study, by which time 5.1% of the Zineb received was excreted as urinary ETU. Faecal ETU disappeared after 3 days.
Descriptors (primary) ethylenethiourea; zineb; exposure tests; fungicides; faecal excretion; urinary excretion
Descriptors (secondary) animal experiments; urinary metabolites
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Biological monitoring
Amides
Agricultural chemicals