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Document ID (ISN)42933
CIS number 84-1964
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1983
Convention or series no.
Author(s) Gribova I.A., Evlaško Ju.P., Pavlovskaja N.A., Semenova L.S., Sorkina N.S.
Title Importance of morphological studies of the blood at various levels of lead exposure
Original title O značenii morfologičeskogo issledovanija krovi pri raznyh urovnjah vozdejstvija svinca [in Russian]
Bibliographic information Feb. 1983, No.2, p.22-25. Illus. 8 ref.
Abstract 520 workers in unspecified industries were divided into 3 groups on the basis of their lead exposure: ambient levels no higher than the USSR MAC, ambient levels transiently exceeding the MAC, and ambient levels routinely exceeding the MAC by an order of magnitude. Lead levels in blood and other tissues were correlated with exposure. The 1st group showed no anaemia, mild reticulocytosis and few cellular abnormalities. 5.0% of the 2nd group were anaemic, but blood morphology was little different from that of the 1st group. The 3rd group contained 8.8% anaemics, and cases of extreme reticulocytosis, with high counts of erythrocytes containing basophilic granules, were encountered. When individual blood and urine lead levels were plotted with reticulocyte and granulated erythrocyte counts, quantitative correlations between lead content and blood-cell abnormalities were clear.
Descriptors (primary) reticulocytes; blood cytology; erythrocyte stippling; lead
Descriptors (secondary) dose-response relationship
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Inorganic substances
Blood diseases
Lead and compounds