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Document ID (ISN)42332
CIS number 84-1372
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 1983
Convention or series no.
Author(s) Andersson R., Carlsson A., Byfält Nordqvist M., Sollenberg J.
Title Urinary excretion of hippuric acid and o-cresol after laboratory exposure of humans to toluene
Bibliographic information Dec. 1983, Vol.53, No.2, p.101-108. Illus. 21 ref.
Abstract Volunteers were exposed to 80ppm toluene for 2h under different workloads for periods of 30min and with varying diet. There was no correlation between total urinary excretion, excretion rate and concentration of the metabolites and respiratory uptake of toluene. Thus neither metabolite was a reliable measure of individual toluene uptake under the conditions of the trial. A number of other factors are considered to influence the fraction of the retained toluene that is excreted as hippuric acid and o-cresol in the urine.
Descriptors (primary) cresols; toluene; exposure tests; urinary metabolites; hippuric acid
Descriptors (secondary) metabolic process; inhalation; human experiments; exercise tests; diet
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Nutrition
Aromatic hydrocarbons
Biological monitoring