| Document ID (ISN) | 42280 |
| CIS number |
84-1357 |
| ISSN - Serial title |
0025-7818 - Medicina del lavoro |
| Year |
1983 |
| Convention or series no. |
|
| Author(s) |
Chiesura Corona P., Trevisan A., Buzzo A., Moretto A. |
| Title |
Biological monitoring of exposure of workers in the cadmium metallurgy |
| Original title |
Monitoraggio biologico dell'esposizione in addetti alla metallurgia del cadmio [in Italian] |
| Bibliographic information |
Sep.-Oct. 1983, Vol.74, No.5, p.404-413. Illus. 18 ref. |
| Abstract |
24 workers classified according to exposure to cadmium during electrolytic extraction were studied. Cadmium exposure was presumed very high in 1975-77 and was near TLV concentrations in 1980, after technical improvements had been undertaken. Blood and urinary cadmium concentrations correlated with cumulative and with current exposure. Urinary proteins, β2-microglobulins and tubular reabsorption of β2-microglobulins showed statistically significant changes in the most exposed group, but there were no clear signs of kidney damage. Urinary enzymes, especially angiotensin-converting enzyme (ACE), correlated well with increasing cadmium load. Urinary loss of a ACE appears to be an early sign of tubular involvement. Results confirm that the biological TLVs (10µg/l Cd in the blood and 10µg/g creatinine for Cd in urine) provide reliable protection. |
| Descriptors (primary) |
exposure tests; electrolysis; non-ferrous metal industries; cadmium |
| Descriptors (secondary) |
enzymes; early diagnosis; renal diseases; urine monitoring; dose-response relationship; blood monitoring; proteinuria |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Inorganic substances
Biological monitoring
Smelting and refining operations
Cadmium and compounds
|
