| Document ID (ISN) | 42213 |
| CIS number |
84-1334 |
| ISSN - Serial title |
0007-1072 - British Journal of Industrial Medicine |
| Year |
1983 |
| Convention or series no. |
|
| Author(s) |
Falck Jr. F.Y., Fine L.J., Smith R.G., Garvey J., Schork A., England B., McClatchey K.D., Linton J. |
| Title |
Metallothionein and occupational exposure to cadmium |
| Bibliographic information |
Aug. 1983, Vol.40, No.3, p.305-313. Illus. 23 ref. |
| Abstract |
53 men occupationally exposed to Cd were studied. Urinary metallothionein (MT) excretion, serum MT levels and serum creatinine concentrations were significantly higher in subjects with abnormal renal function who had been exposed to Cd. MT excretion was linearly related to protein excretion, β2-microglobulin excretion, and cumulative dose. It was a better predictor of dose than either β2-microglobulin excretion or Cd excretion. MT is a potential biological monitor for chronic Cd exposure which would be useful for preventing Cd-induced nephropathy. |
| Descriptors (primary) |
metallothioneins; exposure tests; cadmium; urine monitoring; blood monitoring |
| Descriptors (secondary) |
renal dysfunction; renal diseases; comparative study; dose-response relationship; long-term exposure |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Inorganic substances
Biological monitoring
Cadmium and compounds
|
