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CISDOC database
Document ID (ISN) | 41772 |
CIS number |
84-789 |
ISSN - Serial title |
0096-1736 - Journal of Occupational Medicine |
Year |
1983 |
Convention or series no. |
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Author(s) |
Gibson E.S., McCalla D.R., Kaiser-Farrell C., Kerr A.A., Lockington J.N., Hertzman C., Rosenfeld J.M. |
Title |
Lung cancer in a steel foundry: a search for causation |
Bibliographic information |
Aug. 1983, Vol.25, No.8, p.573-578. Illus. 21 ref. |
Abstract |
An Ames assay of particulate mutagenicity was taken at the pouring floor, core room, bench moulding, chip shop and electric furnace areas of a foundry and in the outside air. Mutagenic activity was found in all foundry areas and was substantially higher than in the outside samples. There was considerable variation within sites, but overall activity was highest in the crane area above the pouring floor, intermediate in the moulding area, and lowest in the electric furnace samples. There was a relatively large direct-acting mutagenic component indicating the presence of compounds other than polycyclic aromatic hydrocarbon (PAH) carcinogens, associated with material >7µm in diameter. PAH carcinogen levels may represent only a fraction of total mutagenicity. |
Descriptors (primary) |
mutagens; carcinogens; foundries; iron and steel industry; lung cancer |
Descriptors (secondary) |
aromatic hydrocarbons; mutagenicity tests; polycyclic hydrocarbons |
Document type |
D - Periodical articles |
Subject(s) |
Occupational pathology
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Broad subject area(s) |
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Browse category(ies) |
Diseases of the respiratory system (except for pneumoconiosis & similar) Foundries, metalcasting and forging operations Iron and steel industry
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