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CISDOC database

Document ID (ISN)41750
CIS number 84-786
ISSN - Serial title 0098-4108 - Journal of Toxicology and Environmental Health
Year 1983
Convention or series no.
Author(s) Kluwe W.M., Haseman J.K., Huff J.E.
Title The carcinogenicity of di(2-ethylhexyl) phthalate (DEHP) in perspective
Bibliographic information July 1983, Vol.12, No.1, p.159-169. Illus. 35 ref.
Abstract A critical review of recent animal studies into the carcinogenicity of di(2-ethylhexyl) phthalate (DEHP) concludes that they were conducted in accordance with state-of-the-art procedures and that the interpretations of the results are valid. Experimental evidence indicates that the plasticiser DEHP is carcinogenic to rats and mice, causing hepatocellular carcinomas. The carcinogenic potential of DEHP in humans requires further study. Firm conclusions concerning health risks of DEHP exposure should be avoided at this time.
Descriptors (primary) carcinogens; toxicology; bis(ethylhexyl) phthalate
Descriptors (secondary) liver cancer; plasticizers; carcinogenic effects; animal experiments
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Phthalates
Esters and salts