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CISDOC database
| Document ID (ISN) | 41466 |
| CIS number |
84-420 |
| ISSN - Serial title |
0098-4108 - Journal of Toxicology and Environmental Health |
| Year |
1982 |
| Convention or series no. |
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| Author(s) |
Miller T.L., Lorusso D.J., Deinzer M.L. |
| Title |
The acute toxicity of nonachloropredioxin and 3- and 4-hydroxynonachlorodiphenyl ether in mice |
| Bibliographic information |
Oct.-Nov. 1982, Vol.10, Nos.4-5, p.699-707. Illus. 24 ref. |
| Abstract |
The acute intraperitoneal LD50 values of hydroxynonachlorodiphenyl ethers (HNDPE), contaminants of technical pentachlorophenol (PCP) wood preservative, were determined in mice and compared with those of PCP and Triclosan, a commonly used bactericide. The acute toxicity decreased in the order 2-hydroxynonachlorodiphenyl ether, PCP, 3-hydroxynonachlorodiphenyl ether, 4-hydroxynonachlorodiphenyl ether, Triclosan. Symptomatology following exposure to HNDPE was similar to that observed for PCP. Technical PCP contains 1-5% of HNDPE which do not contribute significantly to its acute toxicity. |
| Descriptors (primary) |
wood preservatives; impurities; toxicology; pentachlorophenol |
| Descriptors (secondary) |
2,3,4,6-tetrachloro-5-pentachlorophenoxyphenol; 2,3,5,6-tetrachloro-4-pentachlorophenoxyphenol; lethal dose 50; animal experiments; 5-chloro-2-(2,4-dichlorophenoxy)phenol |
| Document type |
D - Periodical articles |
| Subject(s) |
Toxic and dangerous substances
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| Broad subject area(s) |
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| Browse category(ies) |
Alcohols
Environmental pollution
Phenols and phenolic compounds
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