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Document ID (ISN)41440
CIS number 84-417
Year 1984
Convention or series no.
Author(s) Cachat-Delpont M.F.
Title Presently known occupational hazards of acrylonitrile
Original title Risques professionnels actuellement connus concernant l'acrylonitrile [in French]
Bibliographic information Université Pierre et Marie Curie, Faculté de Médecine Saint-Antoine, Paris, France, 1983. 176p. 58 ref.
Abstract This MD thesis summarises the physical and chemical properties, methods of analysis, means of production, industrial uses, possibilities of occupational exposure, metabolism, mechanism of action, fire hazards, and pathological effects of acute, subacute and chronic exposure in man and animals, as well as the methods of detection and determination in the workplace, exposure limits (4ppm for an 8h day, 5 days per week), methods of treatment depending on types of contamination, technical and medical preventive measures, regulations and recommendations covering safety and health in the workplace, neighbourhood protection, transport and waste disposal. Acrylonitrile is a potential carcinogen, as suggested by long-term animal experiments, case studies and epidemiological data. Determination of urinary mercapturic acids seems to be a promising means of biologically monitoring exposed workers.
Descriptors (primary) carcinogens; harmful substances; toxicology; acrylonitrile
Descriptors (secondary) France; metabolic process; neoplasms; sampling and analysis; exposure tests; thesis
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Cyano compounds