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CISDOC database

Document ID (ISN)41370
CIS number 84-467
Year 1983
Convention or series no. Fb 347
Author(s) Piechotta W., Witting U., Miebs T., Witting C., Krieg V., Kollmeier H., Seemann J., Wittig P.
Title Carcinogenic, mutagenic and immunological effects of heavy metals
Original title Cancerogene, mutagene und immunsystem-bezogene Wirkungen von Schwermetallen [in German]
Bibliographic information Bundesanstalt fŘr Arbeitsschutz und Unfallforschung, Postfach 170202, 4600 Dortmund 17, Federal Republic of Germany, 1983. Vol.1: 264p. 300 ref. Price: DM.34.00. Vol.2: 347p. 535 ref. Price: DM.42.00. Vol.3: 93p. 172 ref. Price: DM.20.35.
Abstract The 1st of these 3 reports summarises present knowledge of the harmful effects of lead, cadmium and mercury and reviews the relevant literature: animal experiments, epidemiological studies, in-vitro studies, occupational exposure, defenses against infection, humoral and cellular immunity. Results are summarised in tables. The 2nd report analyses the literature on malignant tumours of occupational origin. Results are tabulated according to the organs and tissues affected: blood and lymphatic tissue, respiratory tract, mesothelioma, digestive system, liver and pancreas, urogenital system, brain, skeleton, skin; occupations and harmful substances are also identified. The 3rd report is a review of various methods of sampling and sample preparation in order to complex and extract heavy metals for flameless atomic absorption spectrophotometry. The metals concerned are: cadmium, chromium, nickel, lead and zinc in human pulmonary, hepatic, splenic and renal tissue. Preferred methods are presented.
Descriptors (primary) mutagenic effects; mercury; zinc; chromium; immunobiological changes; carcinogenic effects; cadmium; lead
Descriptors (secondary) literature survey; mesothelioma; nickel; report; metals; neoplasms; animal experiments; in vitro experiments; sampling and analysis; determination in biological matter; atomic absorption spectrometry; epidemiologic study
Document type E - Books, reports, proceedings
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Mercury and compounds
Cadmium and compounds
Lead and compounds
Inorganic substances