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Document ID (ISN)41313
CIS number 84-394
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1982
Convention or series no.
Author(s) Nizjaeva I.V.
Title Evaluating the health effects of acetone
Original title K gigieničeskoj ocenke acetona [in Russian]
Bibliographic information June 1982, No.6, p.24-28. Illus. 5 ref.
Abstract Analysis of clinical records showed an excess of complications of pregnancy and birth defects of offspring among female industrial workers exposed to acetone. The effects were seen in women exposed to acetone levels well below the USSR MAC (200mg/m3), such as rewinders and twisters, as well as in women exposed to concentrations at or above the MAC, such as workers in the chemical synthesis and spinning of fibres. Exposure of experimental animals to typical industrial concentrations of acetone showed that the compound had embryotoxic effects. It is recommended that the MAC be substantially lowered.
Descriptors (primary) embryotoxic effects; antifertility effects; textile industry; toxicology; acetone
Descriptors (secondary) animal experiments; threshold limit values
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Ketones
Genetic factors in reaction to exposures