| Document ID (ISN) | 40969 |
| CIS number |
83-1947 |
| ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
| Year |
1981 |
| Convention or series no. |
|
| Author(s) |
Oskerko E.F., Klimova Ė.I., Kasatkin A.N. |
| Title |
Toxicity and harmfulness of allyl α-allyloxycarbonyloxyacrylate |
| Original title |
O toksičnosti i opasnosti allil α-alliloksikarboniloksiakrilata [in Russian] |
| Bibliographic information |
Dec. 1981, No.12, p.44-45. 5 ref. |
| Abstract |
The title compound ("3-A"), used for the production of new transparent plastics, was administered to experimental animals by inhalation (mice), intragastric infusion (rats, mice) and topical application to skin and conjunctiva (rabbits). The maximum concentration attainable in air (66-77mg/m3) was not lethal, but did produce morphological changes in the uterus and testes of treated animals. Intragastric administration produced metabolic abnormalities observable as alterations in blood and urine composition. 3-A was also a topical irritant. It is more toxic on chronic than on acute administration. A TLV of 0.01mg/m3 workplace air is recommend. |
| Descriptors (primary) |
threshold limit values; USSR; allyl alpha-allyloxycarbonyloxyacrylate; toxicology; plastics industry; acrylates |
| Descriptors (secondary) |
animal experiments; haematotoxic effects; gonadotropic effects |
| Document type |
D - Periodical articles |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Chemical industry
Plastics industry
Genetic factors in reaction to exposures
Occupational exposure limits
Acrylates
|
