| Document ID (ISN) | 40966 |
| CIS number |
83-2003 |
| ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
| Year |
1981 |
| Convention or series no. |
|
| Author(s) |
Al'berton N.I., Zimin S.A., Džangozina D.M., D'jačenko N.V., Poznjakova V.M., Vil'gel'm L.A., Fomenko V.P., Jakšin V.A. |
| Title |
Parameters of the kallikrein-kinin system in synthetic rubber workers suffering from neurocirculatory dystonia |
| Original title |
Pokazateli kallikrein-kininovoj sistemy u bol'nyh nejrocirkuljatornoj distoniej, rabotajuščih na proizvodstve sintetičeskogo kaučuka [in Russian] |
| Bibliographic information |
Dec. 1981, No.12, p.23-26. 9 ref. |
| Abstract |
Blood levels of kallikrein were elevated and levels of kallikreinogen, kininogen and kininase were reduced (in comparison with control levels) in synthetic rubber workers who suffered from neurocirculatory dystonia as a result of exposure to alpha-methylstyrene and divinyl (butadiene); patients with neurocirculatory dystonia of psychogenic origin showed only an elevation in kallikrein and depression in kininogen. The alterations in enzyme and zymogen levels seen in the rubber workers indicate a disturbance in their liver function. A programme of therapy for these patients should include treatment with inhibitors of the kallikrein-kinin system. |
| Descriptors (primary) |
methylstyrenes; butadiene; synthetic rubber industry; diseases of nervous system; enzyme disturbances |
| Descriptors (secondary) |
circulatory disorders; hepatotoxic effects; kinins; kallikrein; alpha-methylstyrene |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Chemical industry
Plastics industry
Blood diseases
Aliphatic and alicyclic hydrocarbons
Aromatic hydrocarbons
Butadiene
|
