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Document ID (ISN)40634
CIS number 83-1694
ISSN - Serial title 0032-6291 - Pracovní lékařství
Year 1982
Convention or series no.
Author(s) Slováček R., Hůzl F., Sýkora J., Senft V., Kavářová A.
Title Use of polyacrylamide gel electrophoresis for the detection of proteinuria in workers exposed to cadmium
Original title Využití elektroforézy na polyakrylamidovém gelu k charakteristice proteinurie u zaměstnanců v exposici kadmiu [in Czech]
Bibliographic information Aug. 1982, Vol.34, No.6-7, p.209-214. Illus. 15 ref.
Abstract 59 active or retired workers from alkaline-battery or cadmium-oxide plants were examined for proteinuria by electrophoresis of urine samples in the presence of sodium dodecyl sulfate. All cadmium-exposed subjects showed higher urinary levels of low-molecular-weight proteins than did non-exposed controls. This tubular proteinuria was detectable in the absence of subjective symptoms of cadmium poisoning, and in the absence of clinically detectable functional disturbances. Thus, electrophoresis is a sensitive method for the early detection of cadmium poisoning.
Descriptors (primary) proteinuria; electrophoresis; cadmium; exposure tests
Descriptors (secondary) proteins; description of technique; battery and dry cell manufacture
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the kidney and the urinary system
Cadmium and compounds
Inorganic substances
Biological monitoring