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Document ID (ISN)40438
CIS number 83-1706
Year 1983
Convention or series no.
Author(s) Gibaud G.
Title A case of occupational poisoning in an agricultural environment. Use of a herbicide containing Ioxynil. Parallel with other substances acting on cellular respiration.
Original title A propos d'un cas d'intoxication professionnelle en milieu agricole. Utilisation d'une préparation herbicide contenant de l'Ioxynil. Parallèle avec d'autres substances agissant sur la respiration cellulaire. [in French]
Bibliographic information Université Pierre et Marie Curie, Faculté de médecine Broussais - Hôtel-Dieu, Paris, France, 1983. 114p. 45 ref.
Abstract A general review of occupational poisonings, the special features of agricultural poisonings and their prevention and compensation, this medical thesis studies the herbicide presumed responsible for the poisoning ("Belgran" which contains 3 active ingredients - isoproturon, mecoprop and ioxynil - each of which are studied separately); only ioxynil seemed to have been responsible for the toxic action of the product. A detailed clinical account is given of the case and the similarities with other known cases of ioxynil poisoning and of poisoning with nitro- or chloro-derivatives of phenol or cresol which have the same inhibiting action on oxidative phosphorylation. Following a chapter on the physiopathology of the poisoning, a comparison is made with other cases that have occurred during production of the same product. Discussion of various possible aetiologies of the varying symptomatology shown by the patient during the poisoning.
Descriptors (primary) herbicides; acute poisoning; agriculture; toxicology; crop protection; ioxynil
Descriptors (secondary) case study; France; pesticide production; cytotoxic effects; thesis
Document type E - Books, reports, proceedings
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s)
Browse category(ies) Agricultural chemicals
Cyano compounds