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Document ID (ISN)40256
CIS number 83-1392
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1981
Convention or series no.
Author(s) Aristov V.N., Red'kin Ju.V., Bruskin Z.Z., Ogleznev G.A.
Title Experimental data on the mutagenic action of toluene, isopropanol and sulfur dioxide
Original title Ėksperimental'nye dannye o mutagennom dejstvii toluola, izopropanola i sernistogo gaza [in Russian]
Bibliographic information July 1981, No.7, p.33-36. 9 ref.
Abstract The nature and frequency of chromosomal and mitotic aberrations in the bone marrow of albino rats were determined in chronic inhalation experiments with toluene, isopropanol and sulfur dioxide in various concentrations and combinations. The statistical calculations involved in predicting no-effect concentrations of toluene and isopropanol are presented; a non-linear regression equation was used. The proposed method can be used to calculate no-effect concentrations of toxic substances for purposes of TLV determination or correction.
Descriptors (primary) mutagens; toluene; sulfur dioxide; chromosome changes; isopropyl alcohol
Descriptors (secondary) animal experiments; mathematical analysis; determination of exposure limits
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Inorganic sulfur compounds
Alcohols
Aromatic hydrocarbons
Inorganic substances