Document ID (ISN) | 40204 |
CIS number |
83-1324 |
ISSN - Serial title |
0016-9900 - Gigiena i sanitarija |
Year |
1981 |
Convention or series no. |
|
Author(s) |
Arhangel'skij V.I. |
Title |
Hygienic evaluation of dibutyltin bis(trifluoroacetate) |
Original title |
Gigieničeskaja ocenka dibutilditriftoracetatolova [in Russian] |
Bibliographic information |
July 1981, No.7, p.18-19. 4 ref. |
Abstract |
The toxicity of dibutyl di(trifluoroacetate)tin (DBDTT) was determined in acute, subacute, and chronic experiments. Its LD50 was: 53.65 mg/kg for mice, 80.0 mg/kg for male rats, 55.0 mg/kg for female rats, 41.1 mg/kg for newborn rats, and 180.0 mg/kg for rabbits. DBDTT is absorbed by the skin, irritates the mucosa of the eye, and is a cumulative poison. In subacute experiments, DBDTT produced several alterations in blood chemistry. Chronic inhalation experiments with 1mg/m3 DBDTT showed alterations in nervous system and liver function. A concentration of 0.1mg/m3h is apparently close to the threshold limit value. |
Descriptors (primary) |
dibutyltin bis(trifluoroacetate); glass industry; toxicology; organotin compounds |
Descriptors (secondary) |
neurotoxic effects; lethal dose 50; animal experiments; hepatotoxic effects |
Document type |
D - Periodical articles |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
|
Browse category(ies) |
Glass, pottery and related materials
|