ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)40157
CIS number 83-1365
ISSN - Serial title Gigiena truda i professional'nye zabolevanija
Year 1981
Convention or series no.
Author(s) Pen E.A.
Title The diagnostic value of some biochemical parameters at various levels of lead exposure
Original title Diagnostičeskaja informativnost' nekotoryh biohimičeskih pokazatelej pri različnyh urovnjah vozdejstvija svinca [in Russian]
Bibliographic information June 1981, No.6, p.46-48. 6 ref.
Abstract In exposed workers, moderate and high concentrations of lead produce both changes in porphyrin metabolism and disruptions in nitrogen metabolism, especially in the end products of nitrogen metabolism and in urea synthesis. The degree of alteration of nitrogen metabolism is proportional to lead exposure and parallels a reduction in delta-aminolaevulinic acid dehydratase (ALAD) levels. Thus, ALAD activity is a useful indicator of lead exposure level.
Descriptors (primary) lead; ALAD; porphyrin metabolism; nitrogen metabolism; diagnosis
Descriptors (secondary) exposure tests
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Blood diseases
Lead and compounds
Inorganic substances