| Document ID (ISN) | 40156 |
| CIS number |
83-1236 |
| ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
| Year |
1981 |
| Convention or series no. |
|
| Author(s) |
Veličkovskaja T.B., Zykova V.A., Orlova T.N. |
| Title |
Predicting the fibrogenicity of silica-containing dusts from the surface properties of the particles |
| Original title |
Prognozirovanie stepeni fibrogennosti kremnezemsoderžaščih pylej v zavisimosti ot svojstv poverhnosti častic [in Russian] |
| Bibliographic information |
June 1981, No.6, p.34-36. 2 ref. |
| Abstract |
The severity of pneumoconiosis induced in rats by 5 silica-containing dusts was correlated with their adsorptive capacity and zeta-potential. DQ-12 quartz (a common reference material) and Ljubercy silica, with zeta-potentials greater than 20, gave much higher lung dry weights and hydroxyproline and lipid contents than did Ky¿tym, Vodolak, or Onega silicas, which have zeta-potentials of 8 to 13; the latter silicas were still fibrogenic in comparison with controls. The more fibrogenic silicas likewise had higher adsorptive capacities for calcium ions and dichlorodimethylsilane. These physico-chemical properties thus provide a quantitative scale for predicting the risk associated with the mining and handling of silica-containing dusts or powders. |
| Descriptors (primary) |
mineral dust; silica; fibrogenic effects; hazard evaluation; respirable dust |
| Descriptors (secondary) |
dust analysis; animal experiments |
| Document type |
D - Periodical articles |
| Subject(s) |
Dust, aerosols and related diseases
|
| Broad subject area(s) |
|
| Browse category(ies) |
Risk evaluation
|
