Document ID (ISN) | 39933 |
CIS number |
83-1007 |
ISSN - Serial title |
0047-1879 - Japanese Journal of Industrial Health - Sangyō-Igaku |
Year |
1982 |
Convention or series no. |
|
Author(s) |
Katahira T., Teramoto K., Horiguchi S. |
Title |
Experimental studies on the toxicity of tetrahydrofuran administered to animals by repeated inhalation |
Bibliographic information |
1982, Vol.24, No.4, p.379-387. Illus. 37 ref. |
Abstract |
Rats were exposed to 100, 200, 1000 or 5000ppm tetrahydrofuran for 4h/day for 12 weeks. 100 and 200ppm had no significant effects except for slight mucosal irritation. 1000ppm affected liver function as indicated by serum chemistry tests. 5000ppm caused marked local irritant symptoms and morphological damage of the respiratory mucosae, and affected white blood cell counts, blood sugar levels and liver functions. |
Descriptors (primary) |
tetrahydrofuran; inhalation toxicity; chronic toxicity; organic solvents |
Descriptors (secondary) |
hepatotoxic effects; animal experiments; irritation |
Document type |
D - Periodical articles |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
|
Browse category(ies) |
Heterocyclic compounds
|