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Document ID (ISN)39422
CIS number 83-513
ISSN - Serial title 0032-6291 - Pracovní lékařství
Year 1982
Convention or series no.
Author(s) Líška D., Kolesár D., Hladká A., Raiskup J.C.
Title Results of clinical and laboratory tests in workers in metathion EK-50 production
Original title Klinické a laboratórne nálezy u pracovníkov pri výrobe metatiónu EK-50 [in Slovak]
Bibliographic information May 1982, Vol.34, No.5, p.170-175, 38 ref.
Abstract Workers employed in the production and packing of metathion, an insecticide derived from fenitrothion, showed signs of parasympathetic stimulation and a tendency to hypotonia. A slight pseudoneurasthenic syndrome was noted in 33% of women and 15% of men. Psychological test revealed a slight loss of memory, a deterioration in oculomotor coordination, in the coordination of movements and in the sense of orientation, a slowing down of the decision-making processes and of complex sensorimotor responses. Biochemical tests revealed blood cholinesterase inhibition, increased GPT and LDH5 iso-enzyme levels, and significant protein fraction changes. Urinary p-nitro-m-cresol levels determined before and after exposure were 1.54 and 5.61mg/l in men and 4.0 and 6.58mg/l in women. Fenitrothion concentrations in the working area varied from 0.028 to 0.118mg/m3.
Descriptors (primary) neurotoxic effects; insecticides; metathion; pesticide production; biochemical effects
Descriptors (secondary) enzyme disturbances; occupational health survey; exposure evaluation; functional nervous disorders
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the nervous system
Esters and salts
Chemical industry
Agricultural chemicals