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Document ID (ISN)39244
CIS number 83-474
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1983
Convention or series no.
Author(s) Miner J.K., Rom W.N., Livingston G.K., Lyon J.L.
Title Lymphocyte sister chromatid exchange (SCE) frequencies in coke oven workers
Bibliographic information Jan. l983, Vol.25, No.1, p.30-33. Illus. 33 ref.
Abstract Lymphocyte sister chromatid exchange (SCE) frequencies were determined for 12 long-term coke oven workers and 12 other age-matched steelworkers with no coke oven work exposure. All study participants were non-smokers. The exposed group had a mean of 28.9 year's exposure to coke oven emissions. SCE frequencies for the exposed workers ranged from 7.97 to 11.20 SCEs per cell while those for the controls ranged from 6.73 to 10.60 SCEs per cell. The mean SCE frequency for the exposed group was 9.54▒SD1.15 SCEs per cell, and was 14% higher than that of the control group (8.35▒1.09 SCE's per cell, p=0.016). The long-term exposure to coke oven emissions in the coke oven workers is considered possibly to be the explanation for this small difference.
Descriptors (primary) airborne dust; coking plants; chromosome changes; gaseous effluents
Descriptors (secondary) genetic effects; long-term exposure
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Antifertility and prenatal effects
Chemical industry
Genetic factors in reaction to exposures