| Document ID (ISN) | 39186 |
| CIS number |
83-145 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
1981 |
| Convention or series no. |
|
| Author(s) |
Norpoth K., Müller G., Zilius Z., Ulynec U., Travenius S.Z.M. |
| Title |
Sensitive spectrophotometric determination of carcinogenic alpha chloro ethers |
| Bibliographic information |
Nov. 1981, Vol.49, No.2, p.151-155. 8 ref. |
| Abstract |
Chromogens were tested for sensitive determination of chloromethyl methyl ether (CMME) and bis(chloromethyl) ether (BCME). The latter compoud can be determined by means of 2-hydrazono-2,3-dihydro-3-methylbenzotriazole hydrochloride (detection limit 10ng). Colorimetric determination using 4-pyridine carboxaldehyde 2-benzothiazolylhydrazone (PBH) is also highly sensitive (detection limits 10ng and 15ng for BMCE and CMME respectively). Sensitive measurements are also possible by means of the Hantzsch reaction as modified by Nash, using acetyl acetone, ammonium chloride, and acetic acid. Dichloromethyl methyl ether, an analogue of the alkylating carcinogens, did not show measureble reactions in the low concentration range. Using the PHB reaction it is possible to determine BCME in air in concentrations as low as 0.2ppb even after absorption on Porapak Q. |
| Descriptors (primary) |
carcinogens; spectrophotometric colorimetry; spectrophotometry; determination in air; halogenated ethers |
| Descriptors (secondary) |
alkylating substances; bis(chloromethyl) ether; chloromethyl methyl ether |
| Document type |
D - Periodical articles |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Ethers
|
