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Document ID (ISN)39156
CIS number 83-142
ISBN(s) 91-7464-145-X
Year 1982
Convention or series no. Arbete och hälsa 1982:26
Author(s) Edling C., Söderkvist P.
Title Criteria document for threshold limit values: Fluorocarbons
Original title Kriteriedokument för gränsvärden: Fluorocarboner [in Swedish]
Bibliographic information Arbetarskyddsstyrelsen, 171 84 Solna, Sweden, 1982. 38p. 86 ref.
Abstract A literature survey of the health hazards of fluorocarbons (Freons 11, 12, 22 and 113) designed to provide the basis for setting on appropriate TLV for these substances. The main acute effects are on the CNS and heart. A questionnaire survey shaved an excess of CNS symptoms in workers with long-term exposure to Freons 11 and 12. Arrythmia has been reported in experimental animals and palpitations in man following long-term exposure to Freon 22. Liver effects have also been reported. There were no reports of experimental or epidemiological findings of mutagenicity, carcinogenicity of teratogenicity. Freons 11 and 13 are the most toxic of the fluorocarbons studied and should receive particular attention when the TLV is being set.
Descriptors (primary) fluorinated hydrocarbons; determination of exposure limits; toxicology
Descriptors (secondary) neurotoxic effects; literature survey; 1,1,2-trichloro-1,2,2-trifluoroethane; cardiotoxic effects; hepatotoxic effects; dichlorofluoromethane; chlorodifluoromethane; trichlorofluoromethane
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Halogenated hydrocarbons