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Document ID (ISN)38995
CIS number 83-185
ISSN - Serial title 1775-8785 - Archives des maladies professionnelles
Year 1982
Convention or series no.
Author(s) Pekari K., Arsac F., Esmaelzadeh A., Boudène C.
Title Determination of urinary coproporphyrins by high-pressure liquid chromatography, and its importance for preventing chronic lead poisoning
Original title Dosage des coproporphyrines urinaires par chromatographie en phase liquide haute pression - Intérêt pour la prévention du saturnisme [in French]
Bibliographic information 1982, Vol.43, No.6, p.449-454. Illus. 23 ref.
Abstract Description of a simple and rapid method of determining urinary coproporphyrins (UCP): acidification and centrifugation of sample and separation by reverse phase column (C18) chromatography. This method was used for the determination of UCP in 28 workers with occupational lead exposure. There was close correlation with urinary ALA (correlation coefficient of 0.74). UCP determination is adequately sensitive but is lacking in biological specificity; it should therefore be considered only as a back-up test procedure in occupational medicine.
Descriptors (primary) coproporphyrins; exposure tests; urinary coproporphyrin monitoring; lead
Descriptors (secondary) urinary ala monitoring; comparative study; gel chromatography
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Inorganic substances
Biological monitoring
Lead and compounds