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CISDOC database

Document ID (ISN)38766
CIS number 82-1975
ISSN - Serial title Cahiers de médecine du travail - Cahiers voor arbeidsgeneeskunde
Year 1982
Convention or series no.
Author(s) Buchet J.P., Lauwerys R.R.
Title Evaluation of exposure to inorganic arsenic
Original title Evaluation de l'exposition à l'arsenic inorganique [in French]
Bibliographic information Mar. 1982, Vol.19, No.1, p.15-23. Illus. 15 ref.
Abstract A technique for analysis of various forms of arsenic, enabling the metabolism of inorganic arsenic to be studied in man, showed that the urinary excretion of this substance and its metabolites is copious and rapid. Metabolism of the inorganic form is a methylation process leading to the formation of monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA), which are excreted in urine with part of the unchanged inorganic form. Biological surveillance of inorganic arsenic-exposed workers gives valid results when using urinary excretion monitoring for this element, provided that the monitoring method used determines specifically the inorganic form and the metabolites MMA and DMA, and excludes the organic form of marine origin.
Descriptors (primary) arsenic; exposure tests; toxicology
Descriptors (secondary) metabolic process; description of technique; urine monitoring
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Inorganic substances
Biological monitoring
Arsenic and compounds