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CISDOC database

Document ID (ISN)38655
CIS number 82-1915
ISSN - Serial title 0003-2654 - Analyst
Year 1981
Convention or series no.
Author(s) Warwick C.J., Bagon D.A., Purnell C.J.
Title Application of electrochemical detection to the measurement of free monomeric aromatic and aliphatic isocyanates in air by high-performance liquid chromatography
Bibliographic information June 1981, Vol.106, p.676-685. Illus. 19 ref.
Abstract 1-(2-Methoxyphenyl)piperazine is used as the electrogenic reagent in the determination. It forms electrochemically active derivatives with all of the isocyanates of occupational hygiene interest that are readily oxidised at carbon electrodes. These derivatives are strongly absorbing in the ultraviolet region, enabling a combination of electrochemical and ultraviolet detectors to be employed to provide additional qualitative information if required. Comparison is made between the electrochemical detection method and high-performance liquid chromatography - ultraviolet detection methods for isocyanate analysis. The electrochemical detection method was significantly more sensitive than UV detection methods for the determination of phenyl isocyanate, toluene diisocyanate, hexamethylene diisocyanate and (4,4'-diisocyanatodiphenyl)methane in air.
Descriptors (primary) high performance chromatography; determination in air; toxic substances; isocyanates
Descriptors (secondary) ultraviolet spectrophotometry; diphenylmethane diisocyanate; description of technique; hexamethylene diisocyanate; 2,4-tolylene diisocyanate; phenyl isocyanate
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Isocyanates
Cyano compounds