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CISDOC database

Document ID (ISN)38539
CIS number 82-1703
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1981
Convention or series no.
Author(s) Gallagher J.S., Ted Tse C.S., Brooks S.M., Bernstein I.L.
Title Diverse profiles of immunoreactivity in toluene diisocyanate (TDI) asthma
Bibliographic information Sep. 1981, Vol.23, No.9, p.610-616. Illus. 40 ref.
Abstract Possible immunoreactivity to mono- and diisocyanate protein conjugates was evaluated in 15 workers with TDI asthma and 17 normal (non-exposed) volunteers. Leucocyte migration tests and measurement of specific IgE by RAST suggest that isocyanates have the potential for eliciting heterogeneous immune responses in certain subpopulations of exposed workers. Continued contact with isocyanates may be necessary for maintenance of specific immunity.
Descriptors (primary) tolylene diisocyanate; immunology; allergic asthma; autoimmunization
Descriptors (secondary) 2,4-tolylene diisocyanate; allergy tests; radioallergosorbent test; immuno-allergy
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Isocyanates
Cyano compounds
Allergies